Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700383 | 0.89 | CYP19A1 (0.49) | CYP19A1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8700003 | 0.88 | CYP19A1 (0.58) | CYP19A1NPC1RAB9AMAOBMAOA | |
| SCHEMBL8699061 | 0.87 | CYP19A1 (0.57) | CYP19A1 | |
| SCHEMBL8702170 | 0.84 | CYP19A1 (0.43) | CYP19A1MAPTCYP3A4 | |
| SCHEMBL8702825 | 0.82 | CYP19A1 (0.60) | CYP19A1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8697715 | 0.77 | CYP19A1 (0.48) | CYP19A1NPC1RAB9AMAOBMAOA | |
| SCHEMBL8697882 | 0.74 | CYP19A1 (0.40) | CYP19A1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8702199 | 0.74 | CYP19A1 (0.45) | CYP19A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL8698505 | 0.72 | CYP19A1 (0.38) | CYP19A1ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL8700871 | 0.72 | CYP3A4 (0.43) | CYP19A1MAPTMAOBMAOACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | claimed |
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |