SCHEMBL8697459

SCHEMBL8697459

CC(C)(C)NC=N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4549129 0.67
SCHEMBL4969030 0.67
SCHEMBL4969038 0.67
SCHEMBL19072924 0.65
SCHEMBL19624067 0.65
SCHEMBL5489375 0.64
SCHEMBL28433 0.64
SCHEMBL5489373 0.64
SCHEMBL21746096 0.64
SCHEMBL26779 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0472526-B1 5-AMINOCARBONYL-5H-DIBENZO a,d]CYCLOHEPTEN-5,10-IMINES FOR TREATMENT OF EPILEPSY AND COCAINE ADDICTION US HEALTH (US) 1996-05-08 EP claimed
EP-3820869-B1 SPIROCHROMANE DERIVATIVES RICHTER GEDEON NYRT (HU) 2023-08-30 EP disclosed
US-20230219896-A1 CANNABINOID RECEPTOR MEDIATING COMPOUNDS THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2023-07-13 US disclosed
WO-2021183555-A1 OCULAR DRUG DEPOT FOR COMPLEMENT-MEDIATED DISORDERS ACHILLION PHARMACEUTICALS, INC. (US) 2021-09-16 WO disclosed
US-10935699-B2 Shape memory assisted self-healing polymeric amorphous coatings SYRACUSE UNIVERSITY (US) 2021-03-02 US disclosed
US-10787419-B2 Cannabinoid receptor mediating iminopyrazole compounds THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2020-09-29 US disclosed
US-10683270-B2 Cannabinoid receptor mediating compounds THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2020-06-16 US disclosed
WO-2020012422-A1 SPIROCHROMANE DERIVATIVES RICHTER GEDEON NYRT. (HU) 2020-01-16 WO disclosed
US-20190352268-A1 CANNABINOID RECEPTOR MEDIATING COMPOUNDS THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2019-11-21 US disclosed
US-9938301-B2 Dihydropyrimido fused ring derivative as HBV inhibitor QILU PHARMACEUTICAL CO., LTD. (CN) 2018-04-10 US disclosed
US-5686614-A Preparation of chiral 5-aminocarbonyl-5H-dibenzo a,d!cyclohepten-5,10-imines by optical resolution NEUROGEN CORPORATION (US) 1997-11-11 US disclosed
WO-1996032390-A1 PREPARATION OF CHIRAL 5-AMINOCARBONYL-5H-DIBENZO-[a,d]CYCLOHEPTEN-5,10-IMINES BY OPTICAL RESOLUTION NEUROGEN CORPORATION (US) 1996-10-17 WO disclosed
EP-0472526-B1 5-AMINOCARBONYL-5H-DIBENZO a,d]CYCLOHEPTEN-5,10-IMINES FOR TREATMENT OF EPILEPSY AND COCAINE ADDICTION US HEALTH (US) 1996-05-08 EP disclosed
US-5196415-A 5-aminocarbonyl-5H-dibenzo[a.d]cyclohepten-5,10-imines for treatment of epilepsy and cocaine addiction THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1993-03-23 US disclosed
WO-1992019108-A1 TREATMENT OF ALCOHOL WITHDRAWAL SYMPTOMS NATIONAL INSTITUTES OF HEALTH (US) 1992-11-12 WO disclosed
EP-0472526-A4 5-AMINOCARBONYL-5H-DIBENZO A,D)CYCLOHEPTEN-5,10-IMINES FOR TREATMENT OF EPILEPSY AND COCAINE ADDICTION US HEALTH (US) 1992-05-20 EP disclosed
EP-0472526-A1 5-AMINOCARBONYL-5H-DIBENZO a,d]CYCLOHEPTEN-5,10-IMINES FOR TREATMENT OF EPILEPSY AND COCAINE ADDICTION. US HEALTH (US) 1992-03-04 EP disclosed
WO-1990013297-A1 5-AMINOCARBONYL-5H-DIBENZO[a,d]CYCLOHEPTEN-5,10-IMINES FOR TREATMENT OF EPILEPSY AND COCAINE ADDICTION THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1990-11-15 WO disclosed
US-4835164-A HYPOTENSIVE AGENTS A. H. ROBINS COMPANY, INCORPORATED (US) 1989-05-30 US disclosed
EP-0279707-A2 Aryloxymethyl derivatives of nitrogenous heterocyclic methanols and ethers thereof having cardiovascular activity A.H. ROBINS COMPANY, INCORPORATED (US) 1988-08-24 EP disclosed