SCHEMBL8697608

SCHEMBL8697608

Cc1cc(C2(c3cc(C)c(Oc4ccc(N)cc4)c(C)c3)CC(C)CCC2C(C)C)cc(C)c1Oc1ccc(N)cc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TEAD4 Q15561 1/20 0.32
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8588599 0.89
SCHEMBL8588547 0.86 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2TEAD4POLBMAPT
SCHEMBL8196761 0.85 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2TEAD4POLBMAPT
SCHEMBL8702009 0.84 SMN1; SMN2 (0.41) ALDH1A1SMN1; SMN2POLBMAPTTDP1
SCHEMBL8536449 0.77 ALDH1A1 (0.31) ALDH1A1
SCHEMBL8588502 0.77 MAOB (0.42) ALDH1A1SMN1; SMN2POLBMAPT
SCHEMBL8590130 0.76
SCHEMBL8196760 0.75 NCOA1 (0.39) ALDH1A1TDP1
SCHEMBL9353585 0.75 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2TEAD4POLBMAPT
SCHEMBL8698975 0.74 NCOA1 (0.36) ALDH1A1TEAD4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5750789-A FROM CORRESPONDING DIAMINE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-05-12 US disclosed
EP-0710690-A2 Polyimide film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-05-08 EP disclosed
US-5498687-A Unsaturated imide compounds containing alicyclic structure, process for producing the same and intermediate therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-03-12 US disclosed
US-5489669-A FORMED FROM AMINE CONTAINING BIS/4-AMINOPHENOXY/PHENYL GROUPS; SOLUBILITY, DIELECTRICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-06 US disclosed
US-5444165-A Reacting diamino compound with unsaturated dicarboxylic anhydride to form amic acid intermediate, catalytic dehydration-ring closing; solvent soluble, low water absorption and flexibility SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-08-22 US disclosed
EP-0633282-A1 Polyimide and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-11 EP disclosed
US-5326881-A Polymers with good heat resistance, good flexibility and low water absorption SUMITOMO CHEMICAL COMPANY LTD. (JP) 1994-07-05 US disclosed
EP-0595230-A1 Unsaturated imide compounds containing alicyclic structure SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-05-04 EP disclosed