Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696819 | 0.96 | NAAA (0.40) | KDM4EMEN1KMT2ARECQLRET | |
| SCHEMBL28961922 | 0.94 | NAAA (0.42) | RETCES2CES1NAAAALOX15 | |
| SCHEMBL21903818 | 0.94 | NAAA (0.42) | RETCES2CES1NAAAALOX15 | |
| SCHEMBL28353564 | 0.94 | NAAA (0.42) | RETCES2CES1NAAAALOX15 | |
| SCHEMBL3805975 | 0.91 | RET (0.38) | KDM4EMEN1KMT2ARETCES2 | |
| Acetic Acid SCHEMBL29234156 | 0.91 | NAAA (0.40) | KDM4EMEN1KMT2ARECQLCES2 | |
| SCHEMBL28023451 | 0.85 | KDM4E (0.34) | KDM4EMEN1KMT2ARECQLRET | |
| SCHEMBL6273664 | 0.85 | RET (0.39) | KDM4EMEN1KMT2ARETBCHE | |
| SCHEMBL3810658 | 0.82 | MAPT (0.49) | CES1SMN1; SMN2MAPK1 | |
| SCHEMBL28022906 | 0.82 | POLM (0.36) | MEN1KMT2ANAAAALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731464-A | AZIDE INTERMEDIATES | CHISSO CORPORATION (JP) | 1998-03-24 | — | — | US | disclosed |