Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696616 | 0.87 | CYP19A1 (0.50) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8703068 | 0.86 | CYP19A1 (0.36) | CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL8698125 | 0.84 | CYP19A1 (0.48) | CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL8700350 | 0.81 | CYP19A1 (0.72) | CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL8700590 | 0.80 | CYP19A1 (0.44) | CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL8697757 | 0.80 | CYP19A1 (0.49) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8697611 | 0.72 | ALDH1A1 (0.33) | CYP19A1 | |
| SCHEMBL8702647 | 0.71 | CYP19A1 (0.69) | CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL8697952 | 0.69 | IDO1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL8698363 | 0.68 | CYP19A1 (0.45) | CYP19A1CYP11B1CYP11B2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | claimed |
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |