Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SDCBP | O00560 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7791651 | 0.90 | KCNA5 (0.54) | KCNA5HDAC1NAMPTAKT1CTSS | |
| SCHEMBL3750932 | 0.85 | KCNA5 (0.54) | KCNA5HDAC1CTSSCTSKKDM4A | |
| SCHEMBL12050574 | 0.85 | KCNA5 (0.54) | KCNA5HDAC1NAMPTAKT1HDAC10 | |
| SCHEMBL7862318 | 0.84 | KCNA5 (0.53) | KCNA5HDAC1NAMPTHDAC10HDAC6 | |
| SCHEMBL8697069 | 0.82 | KCNA5 (0.47) | KCNA5HDAC1NAMPTAKT1HDAC10 | |
| SCHEMBL12685839 | 0.82 | L3MBTL1 (0.56) | HDAC1NAMPTCTSKHDAC10HDAC6 | |
| SCHEMBL9090245 | 0.82 | KCNA5 (0.47) | KCNA5HDAC1NAMPTAKT1HDAC10 | |
| SCHEMBL8254926 | 0.81 | KCNA5 (0.61) | KCNA5HDAC1NAMPTHDAC10HDAC6 | |
| SCHEMBL2573836 | 0.81 | HDAC1 (0.57) | KCNA5HDAC1NAMPTAKT1KDM4A | |
| SCHEMBL8018113 | 0.79 | KCNA5 (0.56) | KCNA5HDAC1NAMPTCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |