Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glutamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.83 |
| ▸ | BLM | P54132 | 1/20 | 0.83 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.83 |
| ▸ | GSR | P00390 | 2/20 | 0.64 |
| ▸ | GRM8 | O00222 | 2/20 | 0.64 |
| ▸ | GRM6 | O15303 | 2/20 | 0.64 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.64 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.64 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.64 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.64 |
| ▸ | GRM5 | P41594 | 1/20 | 0.64 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.64 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.64 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.64 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.64 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.64 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamine SCHEMBL851614 | 1.00 | ALOX15 (0.83) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL2765120 | 1.00 | ALOX15 (0.83) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL9716079 | 1.00 | ALOX15 (0.83) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL9716082 | 1.00 | ALOX15 (0.83) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL2765188 | 1.00 | ALOX15 (0.83) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL1675307 | 1.00 | ALOX15 (0.83) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL9754277 | 1.00 | ALOX15 (0.83) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL15543979 | 0.98 | ALOX15 (0.79) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL28756768 | 0.96 | ALOX15 (0.76) | ALOX15BLMPMP22KMT2AGSR | |
| Glutamine SCHEMBL27557033 | 0.93 | KMT2A (0.86) | ALOX15BLMPMP22KMT2AGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220354812-A1 | COMPOSITIONS, METHODS, KITS AND SYSTEMS FOR CANCER TREATMENT AND METABOLIC INTERVENTION THERAPY | FILTRICINE, INC. | 2022-11-10 | — | — | US | claimed |
| CN-115029304-A | Human oocyte activator and application thereof | 中国医科大学附属盛京医院 | 2022-09-09 | — | — | CN | claimed |
| US-11369127-B2 | Sweetener and flavor compositions, methods of making and methods of use thereof | EPC NATURAL PRODUCTS CO., LTD. (CN) | 2022-06-28 | — | — | US | claimed |
| US-11147295-B2 | Sweetener and flavor compositions, methods of making and methods of use thereof | EPC NATURAL PRODUCTS, LTD. (CN) | 2021-10-19 | — | — | US | claimed |
| US-20200352196-A1 | SWEETENER AND FLAVOR COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE THEREOF | EPC NATURAL PRODUCTS CO., LTD. (CN) | 2020-11-12 | — | — | US | claimed |
| US-20200337339-A1 | SWEETENER AND FLAVOR COMPOSITIONS, METHODS OF MAKING AND METHODS OF USE THEREOF | EPC NATURAL PRODUCTS CO., LTD. (CN) | 2020-10-29 | — | — | US | claimed |
| EP-3107556-B1 | COMPOSITIONS FOR PREVENTING AND/OR TREATING PATHOLOGICAL CONDITIONS ASSOCIATED WITH ALPHA-GLUCOSIDASE | UNIV LA ROCHELLE (FR) | 2019-04-10 | — | — | EP | claimed |
| CN-105392892-A | Recombinant phage and bacteria detection method | SAMPLE TECH INC | 2016-03-09 | — | — | CN | claimed |
| WO-2015016826-A1 | RUMINANT FEED COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME | BENEMILK OY (FI) | 2015-02-05 | — | — | WO | claimed |
| WO-2015016827-A1 | DIETARY COMPOSITIONS FOR RUMINANTS AND CONTAINERS FOR STORING AND DISPENSING SAME | BENEMILK OY (FI) | 2015-02-05 | — | — | WO | claimed |
| WO-2015016823-A1 | DIETARY PASTE COMPOSITIONS FOR RUMINANTS AND METHODS OF MAKING AND USING THE SAME | BENEMILK OY (FI) | 2015-02-05 | — | — | WO | claimed |
| CN-100339476-C | Hot pepper free spore cell assemblies culture method | BEIJING ACAD AGRIC & FORESTRY (CN) | 2007-09-26 | — | — | CN | claimed |
| US-12029228-B2 | Sweetener and flavor compositions, methods of making and methods of use thereof | EPC Natural Products Co., Ltd (CN) | 2024-07-09 | — | — | US | disclosed |
| US-11985994-B2 | Sweetener and flavor compositions, methods of making and methods of use thereof | EPC Natural Products Co., Ltd (CN) | 2024-05-21 | — | — | US | disclosed |
| CN-117042628-A | Sweetener and flavor compositions containing terpene glycosides | 伊比西(北京)植物药物技术有限公司 | 2023-11-10 | — | — | CN | disclosed |
| US-11793218-B2 | Sweetener and flavor compositions, methods of making and methods of use thereof | EPC NATURAL PRODUCTS CO., LTD. (CN) | 2023-10-24 | — | — | US | disclosed |
| WO-1997026912-A9 | ANTI-CD18 ANTIBODIES FOR USE AGAINST STROKE | — | 1997-11-13 | — | — | WO | disclosed |
| US-5428007-A | Increasing oxygenation in hypoxic cells of normal and tumor tissue | YALE UNIVERSITY (US) | 1995-06-27 | — | — | US | disclosed |
| US-5173426-A | Pure polynucleotide; for increasing tissue oxygenation in patients | YALE UNIVERSITY (US) | 1992-12-22 | — | — | US | disclosed |
| US-5162373-A | Gut Atrophy Prevention, Ornithine, Methionine | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1992-11-10 | — | — | US | disclosed |