Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750489 | 0.88 | AOC3 (0.63) | AOC3ACHETAAR1 | |
| SCHEMBL14587087 | 0.86 | AOC3 (0.64) | AOC3 | |
| SCHEMBL11208105 | 0.86 | AOC3 (0.45) | AOC3 | |
| SCHEMBL14587086 | 0.86 | IDO1 (0.42) | AOC3TAAR1 | |
| SCHEMBL25910678 | 0.86 | SLC22A1 (0.47) | AOC3LMNAHIF1A | |
| SCHEMBL14587100 | 0.86 | AOC3 (0.64) | AOC3HTR6 | |
| SCHEMBL8269660 | 0.84 | LMNA (0.48) | AOC3LMNAMEN1KMT2ATAAR1 | |
| SCHEMBL11915432 | 0.84 | LMNA (0.48) | AOC3LMNAMEN1KMT2ATAAR1 | |
| SCHEMBL1068693 | 0.84 | LMNA (0.48) | AOC3LMNAMEN1KMT2ATAAR1 | |
| SCHEMBL15201759 | 0.82 | LMNA (0.46) | LMNAMEN1KMT2ATAAR1HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008837-A1 | PHENYLBUTANOL DERIVATIVES, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | FARMACON, INC. (US) | 1998-03-05 | — | — | WO | disclosed |