Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 11/20 | 0.57 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.57 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696466 | 0.93 | CD274 (0.55) | CD274PDCD1PTGER4PTGER3PTGER1 | |
| SCHEMBL7335526 | 0.85 | TP53 (0.50) | CD274PDCD1FFAR4MTNR1A | |
| SCHEMBL29174155 | 0.84 | CD274 (0.64) | CD274PDCD1PTGER4PTGER3PTGER1 | |
| SCHEMBL6206188 | 0.82 | PTGER4 (0.58) | CD274PDCD1PTGER4PTGER3PTGER1 | |
| SCHEMBL8696572 | 0.81 | CD274 (0.46) | CD274PDCD1PTGER4PTGER3PTGER1 | |
| SCHEMBL8698313 | 0.79 | CD274 (0.39) | CD274PDCD1PTGER4PTGER3PTGER1 | |
| SCHEMBL8700812 | 0.78 | S1PR1 (0.45) | CD274PDCD1 | |
| SCHEMBL16589154 | 0.77 | PTGER4 (0.53) | PTGER4PTGER3PTGER1PTGER2PTGS1 | |
| SCHEMBL28813902 | 0.77 | FFAR4 (0.53) | CD274PDCD1PTGER4PTGER3PTGER1 | |
| SCHEMBL22591127 | 0.77 | PTGER4 (0.56) | CD274PTGER4PTGER3PTGER1PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |