Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696466 | 0.85 | CD274 (0.55) | CD274PDCD1 | |
| SCHEMBL8696572 | 0.83 | CD274 (0.46) | CD274PDCD1 | |
| SCHEMBL8699097 | 0.78 | CD274 (0.57) | CD274PDCD1 | |
| SCHEMBL8695770 | 0.78 | MTNR1A (0.42) | S1PR1CYP2C9CD274PDCD1 | |
| SCHEMBL8699283 | 0.74 | CD274 (0.44) | CD274PDCD1 | |
| SCHEMBL29045424 | 0.74 | FFAR1 (0.46) | — | |
| SCHEMBL8695083 | 0.72 | CD274 (0.38) | CD274PDCD1 | |
| SCHEMBL3113545 | 0.70 | PTGER1 (0.44) | CD274PDCD1 | |
| SCHEMBL29174155 | 0.70 | CD274 (0.64) | CD274PDCD1 | |
| SCHEMBL7900947 | 0.69 | CYP1A2 (0.52) | S1PR1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |