Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704636 | 0.90 | KMT2A (0.57) | PANK3KMT2AL3MBTL1ATMPOLB | |
| SCHEMBL8702850 | 0.89 | PANK3 (0.56) | PANK3KMT2AL3MBTL1ATMPOLB | |
| SCHEMBL8701257 | 0.88 | MAPT (0.52) | KMT2AL3MBTL1MAPTHTR1AHTR1D | |
| SCHEMBL8701082 | 0.85 | KMT2A (0.43) | KMT2AL3MBTL1POLBMAPTKDM4E | |
| SCHEMBL8701040 | 0.85 | MAPT (0.48) | KMT2AL3MBTL1MAPTHTR1AHTR1D | |
| SCHEMBL8703374 | 0.84 | RBP4 (0.49) | KMT2APOLBMAPTMEN1KDM4E | |
| SCHEMBL8704961 | 0.84 | KMT2A (0.49) | KMT2AL3MBTL1POLBMAPTSMN1; SMN2 | |
| SCHEMBL8705266 | 0.83 | KMT2A (0.52) | PANK3KMT2APOLBNPSR1MAPT | |
| SCHEMBL8702972 | 0.83 | KMT2A (0.48) | KMT2APOLBMAPTMEN1KDM4E | |
| SCHEMBL8699082 | 0.83 | KMT2A (0.48) | KMT2APOLBMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |