Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1505031 | 0.87 | ABL1 (0.51) | ABL1LMNAMEN1KMT2AMAPT | |
| SCHEMBL17040919 | 0.86 | SMN1; SMN2 (0.58) | ABL1LMNAMEN1KMT2AMAPT | |
| SCHEMBL22175914 | 0.85 | MAPT (0.50) | ABL1LMNAMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL1505095 | 0.85 | MAPT (0.50) | ABL1LMNAMEN1KMT2AMAPT | |
| SCHEMBL3142232 | 0.84 | ABL1 (0.51) | ABL1LMNAMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL22164302 | 0.84 | MAPT (0.49) | ABL1LMNAMEN1KMT2AMAPT | |
| SCHEMBL13446708 | 0.84 | NPC1 (0.54) | LMNAKMT2AMAPTGAATSHR | |
| SCHEMBL22176521 | 0.83 | ABL1 (0.48) | ABL1LMNAMEN1KMT2AMAPT | |
| SCHEMBL25337618 | 0.83 | PTGDR (0.56) | ABL1LMNAMEN1KMT2AMAPT | |
| SCHEMBL6421995 | 0.83 | SLC6A4 (0.51) | ABL1LMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792767-A | TREATMENT OF BENIGN PROSTATIC HYPERTROPY | ABBOTT LABORATORIES (US) | 1998-08-11 | — | — | US | disclosed |