Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4360418 | 0.88 | LMNA (0.51) | SMN1; SMN2ALDH1A1LMNAABL1MEN1 | |
| SCHEMBL4364443 | 0.87 | GAA (0.50) | SMN1; SMN2LMNATDP1MEN1KMT2A | |
| SCHEMBL1154092 | 0.86 | KDM4E (0.54) | SMN1; SMN2ALDH1A1HTTLMNAABL1 | |
| SCHEMBL3142232 | 0.86 | ABL1 (0.51) | SMN1; SMN2ALDH1A1LMNAABL1MEN1 | |
| SCHEMBL8699121 | 0.86 | ABL1 (0.55) | SMN1; SMN2ALDH1A1LMNAABL1MEN1 | |
| SCHEMBL759639 | 0.86 | GAA (0.53) | SMN1; SMN2ALDH1A1LMNAABL1TDP1 | |
| SCHEMBL11314652 | 0.85 | TSHR (0.51) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL25337618 | 0.84 | PTGDR (0.56) | ALDH1A1LMNAABL1TDP1MEN1 | |
| SCHEMBL6421995 | 0.84 | SLC6A4 (0.51) | SMN1; SMN2ALDH1A1HTTLMNAABL1 | |
| SCHEMBL1505120 | 0.84 | S1PR4 (0.52) | ALDH1A1LMNAABL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015125785-A1 | PYRAZOLONE DERIVATIVE HAVING MULTIPLE SUBSTITUENTS | 第一三共株式会社 | 2015-08-27 | — | — | WO | disclosed |