Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 9/20 | 0.67 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSPO | P30536 | 1/20 | 0.48 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696938 | 0.89 | CCR2 (0.66) | CCR2SERPINE1PPARGGPR35ALDH1A1 | |
| SCHEMBL8700066 | 0.86 | CCR2 (0.64) | CCR2SERPINE1PPARGGPR35NOD2 | |
| SCHEMBL8697469 | 0.85 | CCR2 (0.63) | CCR2SERPINE1PPARGGPR35 | |
| SCHEMBL5421083 | 0.83 | SERPINE1 (0.81) | CCR2SERPINE1PPARG | |
| SCHEMBL5378162 | 0.82 | CCR2 (1.00) | CCR2GPR35NOD2NOD1ALDH1A1 | |
| SCHEMBL8697141 | 0.81 | CCR2 (0.67) | CCR2SERPINE1PPARGGPR35NOD2 | |
| SCHEMBL29845455 | 0.81 | CCR2 (0.81) | CCR2GPR35NOD2NOD1ALDH1A1 | |
| SCHEMBL3961949 | 0.79 | CCR2 (1.00) | CCR2GPR35 | |
| SCHEMBL8697273 | 0.79 | CCR2 (0.72) | CCR2SERPINE1PPARGGPR35NOD2 | |
| SCHEMBL8700207 | 0.79 | CCR2 (0.60) | CCR2SERPINE1PPARGGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767133-A | Secondary amines as antidiabetic and antiobesity agents | PFIZER INC. (US) | 1998-06-16 | — | — | US | disclosed |