Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699152 | 1.00 | GLA (0.42) | GLAL3MBTL1TSHRKCNK3KCNK9 | |
| SCHEMBL8697851 | 0.94 | GLA (0.46) | GLAL3MBTL1TSHRMAPTALDH1A1 | |
| SCHEMBL8697860 | 0.94 | GLA (0.46) | GLAL3MBTL1TSHRMAPTALDH1A1 | |
| SCHEMBL8698558 | 0.91 | CA12 (0.46) | SMN1; SMN2CA12CA1CA2CA7 | |
| SCHEMBL8698554 | 0.91 | CA12 (0.46) | SMN1; SMN2CA12CA1CA2CA7 | |
| SCHEMBL8701953 | 0.84 | ABCB1 (0.46) | KCNK3KCNK9SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8698464 | 0.81 | TRPA1 (0.41) | TSHRKCNK3KCNK9SMN1; SMN2MAPT | |
| SCHEMBL8698455 | 0.81 | TRPA1 (0.41) | TSHRKCNK3KCNK9SMN1; SMN2MAPT | |
| SCHEMBL8699251 | 0.77 | HCRTR1 (0.41) | GLAL3MBTL1TSHRKCNK3KCNK9 | |
| SCHEMBL8700283 | 0.77 | CA12 (0.43) | SMN1; SMN2CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008837-A1 | PHENYLBUTANOL DERIVATIVES, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | FARMACON, INC. (US) | 1998-03-05 | — | — | WO | disclosed |