Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | KHK | P50053 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3334093 | 0.85 | EPHX2 (0.51) | EPHX2HTR2CHTR3EHTR3BHTR1A | |
| Water SCHEMBL8415043 | 0.83 | EPHX2 (0.50) | EPHX2HTR2CHTR3EHTR3BHTR1A | |
| Hydrochloric Acid SCHEMBL8703350 | 0.83 | EPHX2 (0.50) | EPHX2HTR2CHTR3EHTR3BHTR1A | |
| SCHEMBL8917883 | 0.82 | EPHX2 (0.49) | EPHX2KHKHTR2CHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL9076651 | 0.82 | PARP1 (0.49) | EPHX2HTR2CHTR3EHTR3BHTR1A | |
| SCHEMBL9036740 | 0.80 | EPHX2 (0.55) | EPHX2HTR2CHTR3EHTR3BHTR1A | |
| SCHEMBL8916125 | 0.80 | EPHX2 (0.59) | EPHX2HTR2CHTR3EHTR3BHTR1A | |
| SCHEMBL8919131 | 0.80 | EPHX2 (0.52) | EPHX2HTR2CHTR3EHTR3BHTR1A | |
| SCHEMBL7868168 | 0.78 | EPHX2 (0.48) | EPHX2HTR2CHTR3EHTR3BHTR1A | |
| SCHEMBL8916991 | 0.78 | EPHX2 (0.48) | EPHX2HTR2CHTR3EHTR3BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |