Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.47 |
| ▸ | MERTK | Q12866 | 1/20 | 0.47 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | KHK | P50053 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3334093 | 0.89 | EPHX2 (0.51) | EPHX2FLT3TYRO3MERTKGAS6 | |
| Water SCHEMBL8415043 | 0.87 | EPHX2 (0.50) | EPHX2FLT3TYRO3MERTKGAS6 | |
| Hydrochloric Acid SCHEMBL8703350 | 0.87 | EPHX2 (0.50) | EPHX2FLT3TYRO3MERTKGAS6 | |
| Hydrochloric Acid SCHEMBL9076651 | 0.86 | PARP1 (0.49) | EPHX2FLT3TYRO3MERTKGAS6 | |
| SCHEMBL8919131 | 0.86 | EPHX2 (0.52) | EPHX2FLT3TYRO3MERTKGAS6 | |
| SCHEMBL8699158 | 0.82 | EPHX2 (0.51) | EPHX2HTR2CHTR3EHTR3BHTR1A | |
| SCHEMBL9036740 | 0.81 | EPHX2 (0.55) | EPHX2HTR2CHTR3EHTR3BHTR1A | |
| Propionic Acid SCHEMBL9640910 | 0.81 | PARP1 (0.53) | EPHX2HTR2CHTR3EHTR3BHTR1A | |
| SCHEMBL8916125 | 0.81 | EPHX2 (0.59) | EPHX2HTR2CHRH4HTR3EHTR3B | |
| SCHEMBL7868168 | 0.80 | EPHX2 (0.48) | EPHX2HTR2CHTR3EHTR3BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686610-A | Pyridyl piperazine compound | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-11 | — | — | US | disclosed |
| US-5599930-A | Substituted indoles as anti-AIDS pharmaceuticals | THE UPJOHN COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| EP-0594702-A1 | SUBSTITUTED INDOLES AS ANTI-AIDS PHARMACEUTICALS. | UPJOHN CO (US) | 1994-05-04 | — | — | EP | disclosed |
| WO-1993001181-A1 | SUBSTITUTED INDOLES AS ANTI-AIDS PHARMACEUTICALS | THE UPJOHN COMPANY (US) | 1993-01-21 | — | — | WO | disclosed |
| EP-0507861-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS. | UPJOHN CO (US) | 1992-10-14 | — | — | EP | disclosed |
| WO-1991009849-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | disclosed |