Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8704288 | 0.99 | SMN1; SMN2 (0.47) | GAASMN1; SMN2TMEM97SIGMAR1PYCR1 | |
| SCHEMBL8700961 | 0.94 | SIGMAR1 (0.48) | GAASMN1; SMN2TMEM97SIGMAR1PYCR1 | |
| Hydrochloric Acid SCHEMBL8705540 | 0.93 | SIGMAR1 (0.47) | GAASMN1; SMN2TMEM97SIGMAR1ATM | |
| SCHEMBL8699753 | 0.86 | TMEM97 (0.51) | GAASMN1; SMN2TMEM97SIGMAR1ATM | |
| SCHEMBL8702923 | 0.86 | TSHR (0.53) | SMN1; SMN2SIGMAR1ATMHTR1DHTR1B | |
| SCHEMBL8704864 | 0.86 | ATM (0.55) | GAASMN1; SMN2TMEM97SIGMAR1PYCR1 | |
| Hydrochloric Acid SCHEMBL8699226 | 0.85 | TMEM97 (0.50) | GAASMN1; SMN2TMEM97SIGMAR1ATM | |
| Hydrochloric Acid SCHEMBL8704833 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2SIGMAR1ATMHTR1DHTR1B | |
| SCHEMBL8699293 | 0.84 | HTR1D (0.44) | SMN1; SMN2HTR1DHTR1BTSHRTAAR1 | |
| Hydrochloric Acid SCHEMBL8704210 | 0.84 | ATM (0.53) | GAASMN1; SMN2TMEM97SIGMAR1PYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736568-A | ANTIALLERGENS; IMMUNOMODULANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-04-07 | — | — | US | disclosed |