Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.49 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10866447 | 0.84 | TAAR1 (0.65) | PYCR1TAAR1AOC3ALDH1A1NPSR1 | |
| SCHEMBL15308497 | 0.83 | PYCR1 (0.61) | PYCR1TAAR1CARM1PRMT3PRMT6 | |
| SCHEMBL18917918 | 0.81 | CARM1 (0.69) | PYCR1TAAR1CARM1PRMT3PRMT6 | |
| SCHEMBL27621728 | 0.80 | TAAR1 (0.54) | PYCR1TAAR1CARM1PRMT3PRMT6 | |
| SCHEMBL31404238 | 0.79 | HSD17B10 (0.56) | TAAR1BCHEHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL8815147 | 0.79 | HSD17B10 (0.56) | TAAR1BCHEHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL18918085 | 0.79 | PRMT1 (0.71) | PYCR1TAAR1CARM1PRMT3PRMT6 | |
| SCHEMBL12124968 | 0.79 | PYCR1 (0.65) | PYCR1TAAR1CARM1PRMT3PRMT6 | |
| SCHEMBL2088569 | 0.78 | KDM4E (0.57) | TAAR1AOC3ALDH1A1ACHEHSD17B10 | |
| SCHEMBL7242775 | 0.77 | PYCR1 (0.62) | PYCR1TAAR1CARM1PRMT3PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736568-A | ANTIALLERGENS; IMMUNOMODULANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-04-07 | — | — | US | disclosed |
| EP-0750607-A1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | Knoll AG (DE) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995023127-A1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | KNOLL AG (DE) | 1995-08-31 | — | — | WO | disclosed |