Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14024659 | 0.85 | PYCR1 (0.53) | PYCR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL26675992 | 0.79 | PYCR1 (0.51) | PYCR1SLC6A2SLC6A4SLC6A3IDO1 | |
| SCHEMBL11978824 | 0.76 | PYCR1 (0.56) | PYCR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8680742 | 0.76 | SLC6A4 (0.63) | PYCR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30589200 | 0.76 | SLC6A4 (0.63) | PYCR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8705112 | 0.75 | CHRM2 (0.53) | TAAR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL7365187 | 0.75 | NR4A2 (0.50) | PYCR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL7365186 | 0.75 | NR4A2 (0.50) | PYCR1SLC6A2SLC6A4SLC6A3AOC3 | |
| SCHEMBL13859048 | 0.75 | PYCR1 (0.55) | PYCR1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13416729 | 0.74 | PYCR1 (0.59) | PYCR1TAAR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736568-A | ANTIALLERGENS; IMMUNOMODULANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-04-07 | — | — | US | disclosed |
| EP-0750607-A1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | Knoll AG (DE) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995023127-A1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | KNOLL AG (DE) | 1995-08-31 | — | — | WO | disclosed |