SCHEMBL8699329

SCHEMBL8699329

CCCCCCCCCCCCCCCCCCCCC=CNC=CCCCCCCCCCCCCCCCCCCCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.52
TRPV1 Q8NER1 1/20 0.52
TSHR P16473 2/20 0.46
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
CYP3A4 P08684 2/20 0.45
TERT O14746 3/20 0.45
CYP1A2 P05177 2/20 0.45
MAPT P10636 2/20 0.45
CYP2C19 P33261 2/20 0.45
BLM P54132 2/20 0.45
HSD17B10 Q99714 2/20 0.45
FABP4 P15090 2/20 0.45
PTPN1 P18031 2/20 0.45
PPARG P37231 2/20 0.45
PPARD Q03181 2/20 0.45
PPARA Q07869 2/20 0.45
GMNN O75496 1/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL284562 1.00 FAAH (0.52) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL10626041 1.00 FAAH (0.52) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL3477621 1.00 FAAH (0.52) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL3477623 1.00 FAAH (0.52) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL9630591 1.00 FAAH (0.52) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL7103122 1.00 FAAH (0.52) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL10626046 1.00 FAAH (0.52) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL284561 1.00 FAAH (0.52) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL8699327 1.00 FAAH (0.52) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL22015838 1.00 FAAH (0.52) FAAHTRPV1TSHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0634456-B1 VULCANIZABLE FLUOROELASTOMER COMPOSITION DU PONT (US) 1998-11-18 EP disclosed
US-5508355-A CONTAINING A POLYOL VULCANIZER, ALIPHATIC AMINE AND CATIONIC ACCELERATOR; IMPROVED MOLD RELEASE, WORKABILITY IN INJECTIONMOLDING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-04-16 US disclosed
EP-0634456-A1 VULCANIZABLE FLUOROELASTOMER COMPOSITION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-01-18 EP disclosed