Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | RBP4 | P02753 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699931 | 0.90 | RBP4 (0.52) | MAPTTP53RBP4KMT2AGAA | |
| SCHEMBL8700453 | 0.88 | RBP4 (0.56) | MAPTTP53RBP4KMT2AGAA | |
| SCHEMBL8704891 | 0.88 | MAPT (0.53) | MAPTTP53RBP4ALDH1A1LMNA | |
| SCHEMBL8699435 | 0.88 | RBP4 (0.49) | MAPTTP53RBP4KMT2AGAA | |
| SCHEMBL8703929 | 0.86 | RBP4 (0.47) | MAPTTP53RBP4KMT2AGAA | |
| SCHEMBL8705216 | 0.85 | RBP4 (0.49) | MAPTTP53RBP4KMT2AGAA | |
| SCHEMBL8703304 | 0.85 | MAPT (0.55) | MAPTTP53RBP4KMT2AGAA | |
| SCHEMBL8699306 | 0.85 | MAPT (0.42) | MAPTTP53RBP4KMT2AGAA | |
| SCHEMBL8703466 | 0.85 | MAPT (0.48) | MAPTTP53RBP4KMT2AGAA | |
| SCHEMBL8705260 | 0.84 | RBP4 (0.55) | MAPTRBP4KMT2AGAAPHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |