Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854834 | 0.80 | MAPT (0.54) | MAPTHTTALDH1A1LMNACYP1A2 | |
| SCHEMBL7835308 | 0.79 | GALR2 (0.46) | MAPTHTTALDH1A1LMNAABCG2 | |
| SCHEMBL31477687 | 0.76 | KMT2A (0.52) | MAPTHTTALDH1A1LMNAKMT2A | |
| SCHEMBL1669347 | 0.76 | KMT2A (0.52) | MAPTHTTALDH1A1LMNAKMT2A | |
| SCHEMBL1669351 | 0.76 | KMT2A (0.52) | MAPTHTTALDH1A1LMNAKMT2A | |
| SCHEMBL31455363 | 0.76 | GSK3B (0.43) | MAPTCYP1A2ABCG2KMT2AMEN1 | |
| SCHEMBL12100934 | 0.75 | GSK3B (0.57) | MAPTALDH1A1CYP1A2ABCG2KMT2A | |
| SCHEMBL11241875 | 0.75 | POLB (0.47) | MAPTHTTALDH1A1CYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL9694453 | 0.75 | KMT2A (0.51) | MAPTHTTALDH1A1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL9694444 | 0.75 | KMT2A (0.51) | MAPTHTTALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998045266-A1 | 3-AMINOPYRIDINE DERIVATIVES FOR TREATMENT OF INFLAMMATORY AND MALIGNANT DISEASES | FERRING B.V. (NL) | 1998-10-15 | — | — | WO | disclosed |