Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | AADAC | P22760 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699458 | 0.80 | MAPT (0.51) | MAPTHTTALDH1A1LMNACYP1A2 | |
| SCHEMBL1669347 | 0.76 | KMT2A (0.52) | MAPTHTTALDH1A1LMNAMAPK1 | |
| SCHEMBL1669351 | 0.76 | KMT2A (0.52) | MAPTHTTALDH1A1LMNAMAPK1 | |
| SCHEMBL31477687 | 0.76 | KMT2A (0.52) | MAPTHTTALDH1A1LMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL9694453 | 0.75 | KMT2A (0.51) | MAPTHTTALDH1A1LMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL9694444 | 0.75 | KMT2A (0.51) | MAPTHTTALDH1A1LMNAMAPK1 | |
| SCHEMBL5120739 | 0.73 | ALDH1A1 (0.47) | MAPTHTTALDH1A1HCAR3TSHR | |
| SCHEMBL5120740 | 0.73 | ALDH1A1 (0.47) | MAPTHTTALDH1A1HCAR3TSHR | |
| SCHEMBL9474771 | 0.73 | ALDH1A1 (0.56) | MAPTHTTALDH1A1HCAR3CYP1A2 | |
| SCHEMBL4869291 | 0.73 | ALDH1A1 (0.56) | MAPTHTTALDH1A1HCAR3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0453065-A1 | Triazolopyridine derivatives | ZENECA LIMITED (GB) | 1991-10-23 | — | — | EP | disclosed |