Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702923 | 0.90 | TSHR (0.53) | TSHRSIGMAR1 | |
| Hydrochloric Acid SCHEMBL8704833 | 0.89 | SMN1; SMN2 (0.52) | TSHRSIGMAR1 | |
| SCHEMBL8703744 | 0.87 | TSHR (0.56) | TSHRACHEMAOBSIGMAR1 | |
| Hydrochloric Acid SCHEMBL8698991 | 0.86 | TSHR (0.54) | TSHRACHEMAOBSIGMAR1 | |
| SCHEMBL8699753 | 0.85 | TMEM97 (0.51) | TSHRACHESIGMAR1 | |
| Hydrochloric Acid SCHEMBL8699226 | 0.84 | TMEM97 (0.50) | TSHRACHESIGMAR1 | |
| SCHEMBL13480685 | 0.83 | TSHR (0.77) | TSHRACHEMAOBKCNH2SIGMAR1 | |
| SCHEMBL8704864 | 0.79 | ATM (0.55) | TSHRACHEKCNH2SIGMAR1 | |
| SCHEMBL16039094 | 0.79 | ACHE (0.76) | TSHRACHESIGMAR1SMPD1LTA4H | |
| SCHEMBL29336578 | 0.78 | TSHR (0.69) | TSHRACHEKCNH2SIGMAR1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736568-A | ANTIALLERGENS; IMMUNOMODULANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-04-07 | — | — | US | disclosed |