Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.52 |
| ▸ | PPARG | P37231 | 13/20 | 0.52 |
| ▸ | PPARA | Q07869 | 13/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12442803 | 0.80 | PPARD (0.55) | PPARDPPARGPPARA | |
| SCHEMBL17017214 | 0.77 | PPARD (0.50) | PPARDPPARGPPARANPC1PKM | |
| SCHEMBL17017237 | 0.76 | NPC1 (0.51) | PPARDPPARGPPARANPC1PKM | |
| SCHEMBL17017257 | 0.76 | PPARG (0.50) | PPARDPPARGPPARANPC1PKM | |
| SCHEMBL11305960 | 0.76 | HTT (0.46) | PPARDPPARANPC1RAB9ALMNA | |
| SCHEMBL11309358 | 0.76 | HTT (0.46) | PPARDPPARANPC1RAB9ALMNA | |
| SCHEMBL17017230 | 0.75 | PPARG (0.46) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL17017238 | 0.75 | NPC1 (0.48) | PPARDPPARGPPARANPC1PKM | |
| SCHEMBL11265234 | 0.75 | HTT (0.48) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL11265236 | 0.75 | HTT (0.48) | PPARDPPARGPPARANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773469-A | Diaryl antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-06-30 | — | — | US | disclosed |