Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702327 | 0.81 | PPARA (0.61) | PPARAPPARGGRM2MAPK1L3MBTL1 | |
| SCHEMBL14882747 | 0.80 | PPARA (0.68) | PPARAPPARGKDM4EGAAHSD17B10 | |
| SCHEMBL12504047 | 0.79 | PPARA (0.71) | PPARAPPARGKDM4EGAAHSD17B10 | |
| SCHEMBL4432959 | 0.78 | PPARA (0.69) | PPARAPPARGKDM4EGAAHSD17B10 | |
| SCHEMBL9863137 | 0.77 | PPARA (0.67) | PPARAPPARGKDM4EGAAHSD17B10 | |
| SCHEMBL8699358 | 0.77 | IDO1 (0.39) | MAOB | |
| SCHEMBL12406953 | 0.77 | PPARA (0.67) | PPARAPPARGKDM4EGAAHSD17B10 | |
| SCHEMBL10904428 | 0.77 | PPARA (0.67) | PPARAPPARGKDM4EGAAHSD17B10 | |
| SCHEMBL1910455 | 0.77 | PPARA (0.67) | PPARAPPARGKDM4EGAAHSD17B10 | |
| SCHEMBL5563172 | 0.77 | PPARA (0.67) | PPARAPPARGKDM4EGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008838-A1 | SUBSTITUTED AMINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-03-05 | — | — | WO | disclosed |