SCHEMBL8699358

SCHEMBL8699358

CC(C)(O)COc1cccc(CO[Si](C)(C)C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.39
AGXT P21549 2/20 0.39
F2 P00734 2/20 0.38
GLS O94925 1/20 0.38
MAOB P27338 10/20 0.37
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
BRD4 O60885 1/20 0.35
CCL2 P13500 1/20 0.35
PKM P14618 1/20 0.35
MRGPRX4 Q96LA9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9900879 0.82 IDO1 (0.43) IDO1AGXTF2MAOB
SCHEMBL8698257 0.82 BCHE (0.42) IDO1AGXTMAOBCYP4F2CYP4A11
SCHEMBL15778630 0.81 IDO1 (0.60) IDO1AGXTMAOB
SCHEMBL8699737 0.81 GGPS1 (0.39) IDO1AGXTF2
SCHEMBL8715771 0.81 IDO1 (0.39) IDO1AGXTF2MAOBCYP4F2
SCHEMBL8701740 0.80 IDO1 (0.38) IDO1AGXTF2MAOBCYP4F2
SCHEMBL8699363 0.79 TSHR (0.38) IDO1AGXTF2CYP4F2CYP4A11
SCHEMBL8703174 0.79 MAPK1 (0.41)
SCHEMBL28079112 0.79 IDO1 (0.40) IDO1AGXTF2MAOB
SCHEMBL31385483 0.79 MAOB (0.42) MAOBCYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998008838-A1 SUBSTITUTED AMINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1998-03-05 WO disclosed