Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | PNMT | P11086 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700156 | 0.83 | IDO1 (0.44) | CYP19A1IDO1ADRA2ASIGMAR1PNMT | |
| SCHEMBL8703698 | 0.76 | PNMT (0.45) | ADRA2APNMT | |
| SCHEMBL6612499 | 0.75 | — | — | |
| SCHEMBL8703784 | 0.74 | HTR2C (0.40) | ADRA2AHTR1A | |
| SCHEMBL3263413 | 0.72 | PRCP (0.60) | — | |
| SCHEMBL3940833 | 0.71 | HRH4 (0.38) | — | |
| SCHEMBL25010764 | 0.69 | — | — | |
| SCHEMBL6476895 | 0.69 | — | — | |
| SCHEMBL13406456 | 0.69 | GBA1 (0.40) | — | |
| SCHEMBL15721229 | 0.69 | HRH3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005651-A1 | NOVEL GLUTAMATE RECEPTOR ANTAGONISTS: FUSED CYCLOALKYL QUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1998-02-12 | — | — | WO | disclosed |