Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696293 | 0.84 | NPC1 (0.47) | NPC1MEN1RAB9AKMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL8695560 | 0.83 | NPC1 (0.47) | NPC1MEN1RAB9AKMT2ATDP1 | |
| SCHEMBL8701540 | 0.82 | NPC1 (0.46) | NPC1MEN1RAB9AKMT2ATDP1 | |
| SCHEMBL8696491 | 0.82 | NPC1 (0.46) | NPC1MEN1RAB9AKMT2ATDP1 | |
| SCHEMBL8696608 | 0.82 | NPC1 (0.46) | NPC1MEN1RAB9AKMT2ATDP1 | |
| SCHEMBL8699260 | 0.81 | NPC1 (0.47) | NPC1MEN1RAB9AKMT2ATDP1 | |
| SCHEMBL8698346 | 0.80 | NPC1 (0.44) | NPC1MEN1RAB9AKMT2ATDP1 | |
| SCHEMBL8697809 | 0.79 | NPC1 (0.45) | NPC1MEN1RAB9AKMT2ATDP1 | |
| SCHEMBL8701033 | 0.78 | NPC1 (0.47) | NPC1MEN1RAB9AKMT2ATDP1 | |
| SCHEMBL8698785 | 0.78 | SIGMAR1 (0.40) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |