Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PRCP | P42785 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11262139 | 0.85 | HTR2C (0.50) | HTR2CHTR2BHTTMEN1KMT2A | |
| SCHEMBL11337359 | 0.84 | HTR2C (0.55) | HTR2CHTR2BMEN1KMT2AALDH1A1 | |
| SCHEMBL9824790 | 0.84 | EPHX1 (0.56) | HTR2CHTR2BMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6653324 | 0.84 | HTR2C (0.55) | HTR2CHTR2BMEN1KMT2AALDH1A1 | |
| SCHEMBL23532695 | 0.83 | MEN1 (0.59) | HTR2CHTR2BMEN1KMT2APRCP | |
| SCHEMBL24322897 | 0.83 | MEN1 (0.59) | HTR2CHTR2BMEN1KMT2APRCP | |
| SCHEMBL22127970 | 0.82 | FOLH1 (0.56) | HTR2CHTR2BHTTCPB1 | |
| SCHEMBL22127969 | 0.82 | FOLH1 (0.56) | HTR2CHTR2BHTTCPB1 | |
| SCHEMBL23039366 | 0.82 | CA1 (0.55) | HTR2CHTR2BDPP4DPP8DPP9 | |
| SCHEMBL23039364 | 0.82 | CA1 (0.55) | HTR2CHTR2BDPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741792-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5741799-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |