Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | CTSC | P53634 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941594 | 0.96 | HTR2C (0.59) | HTR2CHTR2BCTSCALDH1A1EPHX1 | |
| SCHEMBL9464997 | 0.84 | ALDH1A1 (0.58) | HTR2CHTR2BCTSCALDH1A1MEN1 | |
| SCHEMBL9464553 | 0.84 | ALDH1A1 (0.58) | HTR2CHTR2BCTSCALDH1A1MEN1 | |
| SCHEMBL8699715 | 0.84 | HTR2C (0.55) | HTR2CHTR2BALDH1A1MEN1KMT2A | |
| SCHEMBL630942 | 0.82 | TSHR (0.61) | HTR2CHTR2BALDH1A1TSHR | |
| SCHEMBL6727374 | 0.82 | TSHR (0.61) | HTR2CHTR2BALDH1A1TSHR | |
| SCHEMBL12479526 | 0.82 | GLA (0.43) | HTR2CHTR2BALDH1A1TSHRGAA | |
| Hydrochloric Acid SCHEMBL630941 | 0.81 | TSHR (0.64) | HTR2CHTR2BALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL630943 | 0.81 | TSHR (0.64) | HTR2CHTR2BALDH1A1TSHR | |
| SCHEMBL28676037 | 0.81 | TSHR (0.60) | HTR2CHTR2BALDH1A1EPHX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4299821-A | HYPOTHERMIC AGENTS, TREATMENT OF NARCOLEPSY | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1981-11-10 | — | — | US | disclosed |