Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699333 | 0.87 | AOC2 (0.47) | AOC2SMN1; SMN2ALDH1A1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL8707259 | 0.85 | AOC2 (0.41) | AOC2SMN1; SMN2ALDH1A1POLBTP53 | |
| SCHEMBL8704334 | 0.85 | AOC2 (0.43) | AOC2SMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL2357788 | 0.84 | CA12 (0.48) | AOC2SMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL8183727 | 0.82 | AOC2 (0.43) | AOC2SMN1; SMN2L3MBTL1GAAMAPT | |
| Hydrochloric Acid SCHEMBL8704074 | 0.81 | SMN1; SMN2 (0.40) | AOC2SMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL7828377 | 0.81 | CA12 (0.48) | AOC2SMN1; SMN2ALDH1A1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL8704455 | 0.81 | AOC2 (0.42) | AOC2SMN1; SMN2L3MBTL1GAAMAPT | |
| Hydrochloric Acid SCHEMBL8704321 | 0.81 | AOC2 (0.42) | AOC2SMN1; SMN2ALDH1A1L3MBTL1LMNA | |
| SCHEMBL8177385 | 0.80 | AOC2 (0.40) | AOC2SMN1; SMN2ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |