SCHEMBL8699746

SCHEMBL8699746

Nc1ccc2c(C(=O)O)cccc2c1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.52
NR4A2 P43354 1/20 0.52
NR4A3 Q92570 1/20 0.52
G6PD P11413 1/20 0.50
CASP7 P55210 1/20 0.50
CASP6 P55212 1/20 0.50
MMP2 P08253 1/20 0.50
CDC25B P30305 2/20 0.46
PTPN1 P18031 1/20 0.44
ALDH1A1 P00352 2/20 0.43
ALOX15 P16050 1/20 0.43
KDM4E B2RXH2 3/20 0.42
KMT2A Q03164 2/20 0.42
GFER P55789 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
PRNP P04156 1/20 0.42
NSD2 O96028 2/20 0.41
HAVCR2 Q8TDQ0 1/20 0.41
POLB P06746 2/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11316899 0.83 KDM4E (0.42) G6PDCASP7CASP6MMP2CDC25B
SCHEMBL29549315 0.82 CDC25B (0.64) NR4A1NR4A2NR4A3G6PDCASP7
SCHEMBL689824 0.82 CDC25B (0.64) NR4A1NR4A2NR4A3G6PDCASP7
SCHEMBL10012443 0.81 NR4A1 (0.67) NR4A1NR4A2NR4A3G6PDCASP7
SCHEMBL11857852 0.81 NR4A1 (0.67) NR4A1NR4A2NR4A3G6PDCASP7
SCHEMBL27985 0.81 NR4A1 (0.73) NR4A1NR4A2NR4A3G6PDCASP7
SCHEMBL29406795 0.81 NR4A1 (0.73) NR4A1NR4A2NR4A3G6PDCASP7
Hydrochloric Acid SCHEMBL10447811 0.80 CDC25B (0.62) NR4A1NR4A2NR4A3G6PDCASP7
Hydrochloric Acid SCHEMBL11552292 0.80 CDC25B (0.62) NR4A1NR4A2NR4A3G6PDCASP7
Hydrochloric Acid SCHEMBL2457250 0.79 NR4A1 (0.70) NR4A1NR4A2NR4A3G6PDCASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998037940-A1 METHOD OF REMOVING IMPURITIES FROM POLYMERS UTILIZING FACILITATED ION EXCHANGE HOECHST CELANESE CORPORATION (US) 1998-09-03 WO disclosed
US-5599639-A Acid-modified polybenzimidazole fuel cell elements HOECHST CELANESE CORPORATION (US) 1997-02-04 US disclosed
US-5264542-A Molding polybenzimidazole by immersion in a bath, sintering, heating and drying HOECHST CELANESE CORP. (US) 1993-11-23 US disclosed
WO-1991007455-A1 SULFOALKYLATION OF HYDROXYETHYLATED POLYBENZIMIDAZOLE POLYMERS HOECHST CELANESE CORPORATION (US) 1991-05-30 WO disclosed
US-4997892-A Sulfalkylation of hydroxyethylated polybenzimidazole polymers HOECHST CELANESE CORP. (US) 1991-03-05 US disclosed
EP-0354040-A2 Membranes prepared from blends of polybenzimidazole with polyarylates HOECHST CELANESE CORPORATION (US) 1990-02-07 EP disclosed
US-4868249-A Cyanoethylation of hydroxyethylated polybenzimidazole polymers HOECHST CELANESE CORP. (US) 1989-09-19 US disclosed
US-4842740-A LESS SUSCEPTIBLE TO MOISTURE AND MORE THERMALLY PROCESSABLE HOECHST CELANESE CORPORATION (US) 1989-06-27 US disclosed
US-4826502-A Sulfonation of hydroxyethylated polybenzimidazole fibers HOECHST CELANESE CORP. (US) 1989-05-02 US disclosed
US-4814228-A Wet spun hydroxyethylated polybenzimidazole fibers HOECHST CELANESE CORPORATION (US) 1989-03-21 US disclosed
US-4452972-A Production of high molecular weight polybenzimidazole with aryl phosphonic acid or aryl phosphinic acid catalyst CELANESE CORPORATION (US) 1984-06-05 US disclosed
US-4452967-A MELT POLYMERIZATION OF AROMATIC CARBOXY DIAMINE CELANESE CORPORATION (US) 1984-06-05 US disclosed
US-4448954-A Single stage production of improved high molecular weight polybenzimidazole with organosilicon halide catalyst. CELANESE CORPORATION (US) 1984-05-15 US disclosed
US-4448955-A Production of improved high molecular weight polybenzimidazole with tin containing catalyst CELANESE CORPORATION (US) 1984-05-15 US disclosed
EP-0103978-A1 Single stage production of improved high molecular weight polybenzimidazole CELANESE CORPORATION (US) 1984-03-28 EP disclosed
EP-0102171-A1 Production of improved high molecular weight polybenzimidazoles CELANESE CORPORATION (US) 1984-03-07 EP disclosed
US-4431796-A HEATING A MELT OF AROMATIC TETRAAMINE AND AROMATIC DICARBOXYLIC AC CELANESE CORPORATION (US) 1984-02-14 US disclosed
EP-0095348-A2 High molecular weight polybenzimidazoles CELANESE CORPORATION (US) 1983-11-30 EP disclosed
US-4414383-A High molecular weight polybenzimidazole preparation with phosphorus containing polymerization catalyst CELANESE CORPORATION (US) 1983-11-08 US disclosed
US-4312976-A Single-stage melt polymerization process for the production of high molecular weight polybenzimidazole CELANESE CORPORATION (US) 1982-01-26 US disclosed