Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | KDM1A | O60341 | 10/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334238 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2NPSR1HRH3EPHX2KDM1A | |
| SCHEMBL25695438 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2NPSR1HRH3EPHX2KDM1A | |
| Hydrochloric Acid SCHEMBL28626845 | 0.83 | SMN1; SMN2 (0.66) | SMN1; SMN2NPSR1HRH3EPHX2KDM1A | |
| SCHEMBL1197466 | 0.82 | SMN1; SMN2 (1.00) | SMN1; SMN2NPSR1HRH3EPHX2KDM1A | |
| SCHEMBL862934 | 0.82 | SMN1; SMN2 (1.00) | SMN1; SMN2NPSR1HRH3EPHX2KDM1A | |
| SCHEMBL25021708 | 0.82 | SMN1; SMN2 (1.00) | SMN1; SMN2NPSR1HRH3EPHX2KDM1A | |
| SCHEMBL1600902 | 0.82 | SMN1; SMN2 (1.00) | SMN1; SMN2NPSR1HRH3EPHX2KDM1A | |
| SCHEMBL14544486 | 0.82 | SMN1; SMN2 (1.00) | SMN1; SMN2NPSR1HRH3EPHX2KDM1A | |
| SCHEMBL13794162 | 0.82 | SMN1; SMN2 (1.00) | SMN1; SMN2NPSR1HRH3EPHX2KDM1A | |
| Hydrochloric Acid SCHEMBL28254537 | 0.80 | SMN1; SMN2 (0.96) | SMN1; SMN2NPSR1HRH3EPHX2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763621-A | Metalloproteinase inhibitors | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |