Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sucrosofate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 16/20 | 0.54 |
| ▸ | FGF1 | P05230 | 9/20 | 0.48 |
| ▸ | FGF2 | P09038 | 6/20 | 0.48 |
| ▸ | VEGFA | P15692 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sucrosofate SCHEMBL28961186 | 0.99 | HPSE (0.55) | HPSEFGF1FGF2VEGFA | |
| Sucrosofate SCHEMBL7325451 | 0.99 | HPSE (0.55) | HPSEFGF1FGF2VEGFA | |
| Sucrosofate SCHEMBL15653532 | 0.97 | HPSE (0.52) | HPSEFGF1FGF2VEGFA | |
| Sucrosofate SCHEMBL15485823 | 0.97 | HPSE (0.52) | HPSEFGF1FGF2VEGFA | |
| Sucrosofate SCHEMBL3086839 | 0.97 | HPSE (0.52) | HPSEFGF1FGF2VEGFA | |
| Sucrosofate SCHEMBL18467935 | 0.78 | FGF1 (0.74) | HPSEFGF1FGF2VEGFA | |
| Sucrosofate SCHEMBL16661862 | 0.78 | FGF1 (0.74) | HPSEFGF1FGF2VEGFA | |
| Sucrosofate SCHEMBL145070 | 0.78 | FGF1 (0.74) | HPSEFGF1FGF2VEGFA | |
| Sucrosofate SCHEMBL145069 | 0.78 | FGF1 (0.74) | HPSEFGF1FGF2VEGFA | |
| Sucrosofate SCHEMBL16661861 | 0.78 | FGF1 (0.74) | HPSEFGF1FGF2VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022114-A1 | A METHOD FOR PROMOTING TISSUE REPAIR | DUMEX-ALPHARMA A/S (DK) | 1998-05-28 | — | — | WO | disclosed |