Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 8/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.34 |
| ▸ | APEX1 | P27695 | 6/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.34 |
| ▸ | RECQL | P46063 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8704980 | 1.00 | POLB (0.34) | POLBL3MBTL1APEX1TDP1RECQL | |
| Guanidine SCHEMBL8700193 | 0.89 | POLB (0.36) | POLBL3MBTL1APEX1TDP1RECQL | |
| Guanidine SCHEMBL8704972 | 0.89 | POLB (0.36) | POLBL3MBTL1APEX1TDP1RECQL | |
| SCHEMBL7822733 | 0.81 | POLB (0.35) | POLBL3MBTL1APEX1TDP1RECQL | |
| SCHEMBL7815872 | 0.81 | POLB (0.35) | POLBL3MBTL1APEX1TDP1RECQL | |
| SCHEMBL8700691 | 0.77 | AOC2 (0.40) | POLBL3MBTL1APEX1TDP1RECQL | |
| SCHEMBL7826960 | 0.77 | TP53 (0.48) | L3MBTL1MAPTMAPK1TP53ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8700230 | 0.76 | AOC2 (0.39) | POLBL3MBTL1APEX1TDP1RECQL | |
| Maleic Acid SCHEMBL8704977 | 0.76 | POLB (0.37) | POLBL3MBTL1APEX1TDP1RECQL | |
| Fumaric Acid SCHEMBL8700198 | 0.76 | POLB (0.37) | POLBL3MBTL1APEX1TDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |