Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701523 | 1.00 | MAPT (0.42) | MAPTPOLBRECQLTDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8700510 | 0.99 | MAPT (0.41) | MAPTPOLBRECQLTDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8699955 | 0.99 | MAPT (0.41) | MAPTPOLBRECQLTDP1L3MBTL1 | |
| SCHEMBL8706114 | 0.79 | CYP1A2 (0.39) | MAPTPOLBRECQLTDP1L3MBTL1 | |
| SCHEMBL8705201 | 0.75 | CYP1A2 (0.36) | MAPTPOLBRECQLTDP1L3MBTL1 | |
| SCHEMBL8700219 | 0.74 | MAPT (0.42) | MAPTPOLBRECQLTDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL8699950 | 0.73 | MAPT (0.41) | MAPTPOLBRECQLTDP1L3MBTL1 | |
| SCHEMBL1389017 | 0.66 | POLB (0.70) | MAPTPOLBRECQLTDP1L3MBTL1 | |
| SCHEMBL1389018 | 0.66 | POLB (0.70) | MAPTPOLBRECQLTDP1L3MBTL1 | |
| SCHEMBL7825568 | 0.66 | POLB (0.70) | MAPTPOLBRECQLTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |