Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8699950 | 0.99 | MAPT (0.41) | MAPTMAPK1TDP1L3MBTL1NSD2 | |
| SCHEMBL8706111 | 0.77 | ALDH1A1 (0.39) | MAPTTDP1L3MBTL1POLBAPEX1 | |
| SCHEMBL8700223 | 0.74 | MAPT (0.42) | MAPTMAPK1TDP1L3MBTL1NSD2 | |
| SCHEMBL8701523 | 0.74 | MAPT (0.42) | MAPTMAPK1TDP1L3MBTL1NSD2 | |
| Hydrochloric Acid SCHEMBL8699955 | 0.73 | MAPT (0.41) | MAPTMAPK1TDP1L3MBTL1NSD2 | |
| SCHEMBL6933112 | 0.70 | ALDH1A1 (0.57) | MAPTPOLBHSD17B10CTDSP1CYP1A2 | |
| SCHEMBL5674172 | 0.64 | RAB9A (0.57) | POLBHSD17B10CTDSP1KDM4EALDH1A1 | |
| SCHEMBL8634915 | 0.64 | ALDH1A1 (0.55) | MAPTMAPK1POLBHSD17B10CTDSP1 | |
| SCHEMBL6651796 | 0.64 | ALDH1A1 (0.50) | MAPTL3MBTL1POLBHSD17B10CYP1A2 | |
| SCHEMBL9701780 | 0.63 | ALDH1A1 (0.58) | MAPTTDP1L3MBTL1POLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |