SCHEMBL8700244

SCHEMBL8700244

CC(=O)N1COCN=C1N[N+](=O)[O-]

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL422028 0.79 POLB (0.32) POLBSMN1; SMN2
SCHEMBL422862 0.72 POLB (0.30) POLBSMN1; SMN2
SCHEMBL424803 0.72 POLB (0.33) POLBSMN1; SMN2
SCHEMBL422985 0.70 POLB (0.34) POLBSMN1; SMN2
Desmethylthiamethoxam SCHEMBL8706857 0.64 MAPT (0.36) POLBSMN1; SMN2
SCHEMBL1027661 0.56
SCHEMBL492195 0.53
Ammonia Solution, Strong SCHEMBL9456290 0.51
Nitroanilide SCHEMBL2223118 0.51 NAPRT (0.48) POLBSMN1; SMN2
SCHEMBL16136807 0.50 SMN1; SMN2 (0.55) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998006710-A1 SUBSTITUTED 4-NITROIMINO-PERHYDRO-1,3,5-OXADIAZINE DERIVATIVES, THEIR USE AS PESTICIDES AND INTERMEDIATES FOR THEIR PREPARATION NOVARTIS AG (CH) 1998-02-19 WO disclosed