SCHEMBL870026

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL870027	1.00	PDE4B (0.45)	PDE4BHPGDSKCNH2EGLN1CNR2
	SCHEMBL870787	0.93	PDE4B (0.46)	PDE4BHPGDSKCNH2EGLN1PDE4D
	SCHEMBL870786	0.93	PDE4B (0.46)	PDE4BHPGDSKCNH2EGLN1PDE4D
	SCHEMBL872121	0.93	PDE4B (0.47)	PDE4BHPGDSKCNH2EGLN1PDE4D
	SCHEMBL871984	0.93	PDE4B (0.47)	PDE4BHPGDSKCNH2EGLN1PDE4D
	SCHEMBL870702	0.92	PDE4B (0.45)	PDE4BHPGDSKCNH2CNR2PDE4D
	SCHEMBL870703	0.92	PDE4B (0.45)	PDE4BHPGDSKCNH2CNR2PDE4D
	SCHEMBL870690	0.92	PDE4B (0.43)	PDE4BHPGDSCNR2CNR1
	SCHEMBL8169010	0.92	PDE4B (0.43)	PDE4BHPGDSCNR2CNR1
	SCHEMBL870691	0.92	PDE4B (0.43)	PDE4BHPGDSCNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.