Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 7/20 | 0.49 |
| ▸ | RELA | Q04206 | 7/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14153070 | 1.00 | GAA (0.50) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL22618513 | 0.78 | NAAA (0.52) | — | |
| SCHEMBL22618498 | 0.78 | NAAA (0.52) | — | |
| SCHEMBL20279960 | 0.78 | NAAA (0.52) | — | |
| SCHEMBL4949895 | 0.77 | GAA (0.55) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL518197 | 0.74 | GAA (0.60) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL555941 | 0.74 | GAA (0.60) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL9392474 | 0.74 | GAA (0.60) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL15341563 | 0.74 | NAAA (0.51) | GAANFKB1NFKB2RELA | |
| SCHEMBL8294391 | 0.74 | GAA (0.52) | GAANFKB1NFKB2RELABTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750506-A | TREATING INFLAMMATION, HEAD TRAUMA, PAIN, ASTHMA | CORTECH, INC. (US) | 1998-05-12 | — | — | US | disclosed |