Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696581 | 0.89 | CYP19A1 (0.65) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL8697681 | 0.87 | CYP19A1 (0.78) | CYP19A1 | |
| SCHEMBL8702825 | 0.87 | CYP19A1 (0.60) | CYP19A1CYP3A4 | |
| SCHEMBL8696315 | 0.84 | CYP19A1 (0.57) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL8699061 | 0.82 | CYP19A1 (0.57) | CYP19A1 | |
| SCHEMBL8703062 | 0.76 | CYP19A1 (0.58) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL27282169 | 0.76 | CYP19A1 (0.86) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL10837781 | 0.75 | CYP19A1 (0.57) | CYP19A1 | |
| SCHEMBL9651054 | 0.75 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL8700484 | 0.74 | CYP19A1 (0.57) | CYP19A1CYP3A4CYP3A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | claimed |