Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 17/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698102 | 0.91 | CYP19A1 (0.51) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL8697545 | 0.87 | CYP19A1 (0.57) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL8702833 | 0.87 | CYP19A1 (0.57) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL8700497 | 0.84 | CYP19A1 (0.43) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL8699069 | 0.82 | CYP19A1 (0.57) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL27282169 | 0.79 | CYP19A1 (0.86) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL8698122 | 0.76 | CYP19A1 (0.44) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL9651054 | 0.75 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL8700459 | 0.74 | CYP19A1 (0.78) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL8697420 | 0.74 | CYP19A1 (0.66) | CYP19A1CYP3A4CYP3A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | claimed |
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |