Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | VDR | P11473 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712753 | 0.87 | HTR6 (0.60) | HTR6CA1CA2CA7CA9 | |
| SCHEMBL9418437 | 0.84 | HTR6 (0.53) | HTR6CA1CA2CA7CA9 | |
| SCHEMBL27368759 | 0.83 | HTR6 (0.56) | HTR6CA1CA2CA7CA9 | |
| SCHEMBL31352974 | 0.82 | HTR6 (0.77) | HTR6CA1CA2CA7CA9 | |
| SCHEMBL28342639 | 0.82 | HTR6 (0.55) | HTR6CA1CA2CA7CA9 | |
| Hydrochloric Acid SCHEMBL28181401 | 0.82 | HTR6 (0.55) | HTR6CA1CA2CA7CA9 | |
| SCHEMBL8711034 | 0.80 | HTR6 (0.53) | HTR6CA1CA2CA7CA9 | |
| SCHEMBL8713487 | 0.80 | HTR6 (0.53) | HTR6CA1CA2CA7CA9 | |
| SCHEMBL498677 | 0.80 | HTR6 (0.62) | HTR6CA1CA2CA7CA9 | |
| SCHEMBL69581 | 0.80 | HTR6 (0.62) | HTR6CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760191-A | Macrocyclic complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | NYCOMED IMAGING AS (NO) | 1998-06-02 | — | — | US | disclosed |