Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 4/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820341 | 1.00 | CCKBR (0.81) | CCKBR | |
| SCHEMBL6888256 | 1.00 | CCKBR (0.81) | CCKBR | |
| SCHEMBL6887146 | 0.91 | CCKBR (0.77) | CCKBR | |
| SCHEMBL7662872 | 0.89 | CCKBR (0.84) | CCKBR | |
| SCHEMBL7662877 | 0.89 | CCKBR (0.84) | CCKBR | |
| SCHEMBL7664481 | 0.88 | CCKBR (0.83) | CCKBR | |
| SCHEMBL7664489 | 0.88 | CCKBR (0.83) | CCKBR | |
| SCHEMBL9294096 | 0.87 | CCKBR (0.68) | CCKBR | |
| SCHEMBL7665480 | 0.86 | CCKBR (0.84) | CCKBR | |
| SCHEMBL7665470 | 0.86 | CCKBR (0.84) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846942-A | Cholecystokinin antagonists, their preparation and therapeutic use | WARNER-LAMBERT COMPANY (US) | 1998-12-08 | — | — | US | disclosed |
| US-5593967-A | Cholecystokinin antagonists, their preparation and therapeutic use | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| EP-0749422-A1 | INDOLE DERIVATIVES AS CCK RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1996-12-27 | — | — | EP | disclosed |
| US-5508432-A | TREATING GASTROINTESTINAL DISORDERS, CENTRAL NERVOUS SYSTEM DISORDERS | GLAXO WELLCOME INC. (US) | 1996-04-16 | — | — | US | disclosed |
| WO-1995024389-A1 | INDOLE DERIVATIVES AS CCK RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-09-14 | — | — | WO | disclosed |
| US-5380872-A | Appetite suppresant, gall bladder disorders, CNS disorders | GLAXO INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0547178-A4 | NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE | WARNER LAMBERT CO (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0547178-A1 | NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE | WARNER-LAMBERT COMPANY (US) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992004045-A1 | NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |