Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 11/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8703698 | 0.88 | PNMT (0.45) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL8700156 | 0.78 | IDO1 (0.44) | PNMTADRA2A | |
| SCHEMBL12355694 | 0.74 | PNMT (0.57) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL8699075 | 0.73 | — | — | |
| SCHEMBL2246074 | 0.70 | PNMT (0.62) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL31683946 | 0.70 | PNMT (0.64) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL8667327 | 0.70 | PNMT (0.50) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL8500277 | 0.68 | GRIA1 (0.47) | — | |
| SCHEMBL8506553 | 0.68 | GRIA1 (0.34) | — | |
| SCHEMBL6669085 | 0.67 | PNMT (0.51) | PNMTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005651-A1 | NOVEL GLUTAMATE RECEPTOR ANTAGONISTS: FUSED CYCLOALKYL QUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1998-02-12 | — | — | WO | disclosed |