Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | ATM | Q13315 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653829 | 0.92 | KMT2A (0.55) | KMT2AATMPKMALDH1A1KDM4E | |
| SCHEMBL6652670 | 0.90 | PHGDH (0.58) | KMT2AATMALDH1A1KDM4EGAA | |
| SCHEMBL8704636 | 0.90 | KMT2A (0.57) | KMT2AATMALDH1A1KDM4EMAPT | |
| SCHEMBL6657797 | 0.87 | KMT2A (0.48) | KMT2AATMPKMALDH1A1KDM4E | |
| SCHEMBL6652409 | 0.87 | KMT2A (0.48) | KMT2AATMPKMALDH1A1GAA | |
| SCHEMBL6651274 | 0.86 | MEN1 (0.54) | KMT2AALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL8699351 | 0.84 | ALDH1A1 (0.66) | KMT2AALDH1A1KDM4EHTTGAA | |
| SCHEMBL6654791 | 0.83 | PHGDH (0.43) | KMT2AATMALDH1A1KDM4EMAPT | |
| SCHEMBL6657804 | 0.83 | SMN1; SMN2 (0.46) | KMT2AATMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6653052 | 0.82 | PHGDH (0.56) | KMT2APKMALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |