Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 10/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814471 | 0.78 | GRM5 (0.47) | GRM5GRM2NLRP3MAPT | |
| SCHEMBL8595324 | 0.73 | GRM2 (0.62) | GRM2 | |
| SCHEMBL8595322 | 0.73 | GRM2 (0.62) | GRM2 | |
| SCHEMBL3207934 | 0.71 | GRM2 (0.50) | GRM2 | |
| SCHEMBL15686429 | 0.71 | GRM2 (0.50) | GRM2 | |
| SCHEMBL9048647 | 0.71 | NLRP3 (0.38) | GRM2NLRP3 | |
| SCHEMBL8991395 | 0.70 | MAPT (0.45) | GRM2ALDH1A1MAPT | |
| SCHEMBL15066254 | 0.69 | F10 (0.61) | GRM2 | |
| SCHEMBL15066255 | 0.69 | F10 (0.61) | GRM2 | |
| SCHEMBL15084214 | 0.69 | GRM2 (0.46) | GRM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843967-A | 6-membered nitrogen-containing heteroaryl-oxazolidinones | BAYER AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |
| US-5627181-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0694543-A1 | 6-membered N-heteroaryloxazolidinones | BAYER AG (DE) | 1996-01-31 | — | — | EP | disclosed |