Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATP4A | P20648 | 1/20 | 0.31 |
| ▸ | ATP4B | P51164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SCN4A | P35499 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701234 | 0.86 | KDM4E (0.31) | KDM4ESMN1; SMN2MAPTSCN4A | |
| SCHEMBL13604600 | 0.77 | PDCD1 (0.34) | KDM4EMEN1KMT2AATP4AATP4B | |
| SCHEMBL6989900 | 0.76 | NOTUM (0.33) | KDM4E | |
| SCHEMBL20983501 | 0.74 | CYP3A4 (0.33) | CYP1A2SMN1; SMN2 | |
| SCHEMBL7698624 | 0.73 | TSHR (0.44) | KDM4EMAPTALOX15 | |
| SCHEMBL5231523 | 0.73 | PTPN1 (0.36) | KDM4EMEN1KMT2A | |
| SCHEMBL7717808 | 0.72 | PTGIR (0.31) | — | |
| SCHEMBL18787482 | 0.72 | CA12 (0.36) | KDM4EKMT2A | |
| SCHEMBL7779651 | 0.71 | PTGIR (0.35) | — | |
| SCHEMBL3648110 | 0.70 | ADORA2A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827868-A | Prostaglandin analogs | E. R. SQUIBB & SONS, INC. (US) | 1998-10-27 | — | — | US | disclosed |